Allergic Rhinitis (AR) is an IgE mediated immunologic response of nasal mucosa to air borne allergens and is characterized by watery nasal discharge, nasal obstruction, sneezing and itching in the nose. It is clinically divided into two types:-
- Seasonal: Symptoms occur in spring season or when the pollens of plant to which a person is sensitive to is present in the air
- Perennial: When the symptoms occur round the year
- Symptoms of Seasonal AR:paroxysmal sneezing, 10-20 sneezes at a time, nasal obstruction, watery nasal discharge and itching in the nose
- Symptoms of Perennial AR:frequent colds, persistently stuffy nose, anosmia due to mucosal edema, chronic cough and hearing impairment
Treatment limitations and side effects:
Avoid intake of allergens, antihistaminic, gluco corticoids, anti leukotrienes, decongestants, anti-cholinergic and immunotherapy. Such treatment may cause varying degree of sedation or day time drowsiness making negative impact on daily activities and quality of life. Some of the drugs can cause undesirable adverse effects if used for long duration.
In the above backdrop a herbo-mineral ayurvedic formulation IMMBO was studied on 180 patients of Persistent AR in comparison to levocetrizine under the supervision of a senior ENT surgeon in a hospital for 12 weeks.
These patients were divided into three groups, 60 patients received IMMBO in group A while other two groups B &C received levocetrizine 10mg per day and IMMBO+Levocetrizine 10 mg per day respectively. The findings indicate that IMMBO brings significant relief to Persistent AR with minimal side effects.